Description

3β,5-Bis(Trimethylsiloxy)-5α-Cholestane is a high-purity, organosilicon-modified steroidal intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key protected synthon, enabling precise chemical transformations in the production of complex steroid derivatives and other bioactive molecules. It is primarily needed by research institutions and pharmaceutical development teams working on novel therapeutic agents, as well as by fine chemical manufacturers specializing in custom synthesis and high-value intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical protected building block in the multi-step synthesis of novel steroid-based drugs and hormone analogs.
• Research & Development: Used in academic and industrial R&D for studying sterol chemistry, reaction mechanisms, and developing new synthetic methodologies.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialized steroidal compounds for biological testing and material science applications.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3β,5-Bis(Trimethylsiloxy)-5α-Cholestane
CAS No.	33283-15-7
Molecular Formula	C33H62O2Si2
Molecular Weight	546.99 g/mol
Synonyms	5α-Cholestane-3β,5-diol, 3,5-bis(trimethylsilyl) ether; 3β,5-Bis-O-(trimethylsilyl)-5α-cholestane; Cholestane-3β,5-diol bis(trimethylsilyl) ether; 5α-Cholestane-3β,5-diol bis(trimethylsilyl) ether; 3β,5α-Bis(trimethylsiloxy)cholestane; 3,5-Bis(trimethylsiloxy)-5α-cholestane
EINECS	Contact for details

Quality Control

Our 3β,5-Bis(Trimethylsiloxy)-5α-Cholestane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.