Description

[(5β-Pregnane-3α,6α-Diyl)Bis(Oxy)]Bis(Trimethylsilane) is a high-purity, organosilicon-protected steroid derivative, serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its primary value lies in enabling precise chemical transformations by protecting sensitive hydroxyl groups during multi-step synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly those developing novel steroid-based therapeutics, hormone analogs, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex steroid molecules and hormone analogs.
• Research & Development: Used in medicinal chemistry for the exploration of new drug candidates and metabolic pathways.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Protecting Group Chemistry: Serves as a robust protecting agent for diol functionalities in sensitive organic syntheses.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	[(5β-Pregnane-3α,6α-Diyl)Bis(Oxy)]Bis(Trimethylsilane)
CAS No.	33283-07-7
Molecular Formula	C26H50O2Si2
Molecular Weight	450.85 g/mol
Synonyms	3α,6α-Bis(trimethylsilyloxy)-5β-pregnane; 5β-Pregnane-3α,6α-diol bis(trimethylsilyl) ether; Pregnane-3α,6α-diol bis(TMS ether); 3α,6α-Di-O-trimethylsilyl-5β-pregnane; TMS ether of 5β-pregnane-3α,6α-diol; Steroid silyl ether intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(5β-Pregnane-3α,6α-Diyl)Bis(Oxy)]Bis(Trimethylsilane) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.