Description

Digitoxigenin-Galactose is a specialized glycosylated derivative of the cardenolide digitoxigenin, where a galactose sugar moiety is attached. This structural modification is of significant interest for enhancing the solubility, bioavailability, and targeted delivery of the potent cardiac glycoside precursor. It serves as a crucial intermediate and reference standard in pharmaceutical research and development, particularly for investigating novel cardioprotective agents and targeted cancer therapies. This compound is essential for R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors focusing on advanced drug discovery and formulation.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for developing novel cardioprotective drugs and targeted cancer therapeutics.
• Biochemical Research: Used as a reference standard and probe in studies of Na+/K+-ATPase inhibition and cell signaling pathways.
• Drug Discovery: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic profile of cardenolide derivatives.
• Formulation Development: Investigated for its potential to improve the solubility and targeted delivery of hydrophobic active pharmaceutical ingredients (APIs).
• Analytical Standard: Serves as a high-purity calibration standard for HPLC, LC-MS, and other analytical methods in quality control laboratories.

Basic Information

Product Name	Digitoxigenin-Galactose
CAS No.	33275-60-4
Molecular Formula	C29H42O9
Molecular Weight	534.64 g/mol
Synonyms	Digitoxigenin galactoside; 3β-[(6-Deoxy-α-L-galactopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; 3-[(6-Deoxy-α-L-galactopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; Digitoxigenin α-L-galactoside; Strophanthidin α-L-rhamnoside (related structure); Card-20(22)-enolide, 14-hydroxy-3-[(6-deoxy-α-L-galactopyranosyl)oxy]-, (3β,5β)-; α-L-Rhamnosyl digitoxigenin
EINECS	Contact for details

Quality Control

Our Digitoxigenin-Galactose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.