Description

1,2-Cyclohexanedicarbonyl Dichloride, trans-(+)- (9Ci) is a high-purity, stereochemically defined acid chloride derivative of cyclohexane-1,2-dicarboxylic acid. This compound matters as a critical chiral building block and coupling agent in advanced organic synthesis, enabling the precise construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as asymmetric synthesis and polymer modification.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the trans-1,2-cyclohexanedioyl moiety.
• Asymmetric Catalyst Ligand Preparation: Used in the manufacture of precursors for chiral ligands and organocatalysts.
• Polymer Modification: Acts as a monomer or cross-linking agent for producing specialty polyamides, polyesters, and coatings with enhanced thermal or mechanical properties.
• Agrochemical Synthesis: Employed in the production of advanced, stereospecific herbicides and fungicides.
• Peptide & Protein Chemistry: Functions as a coupling reagent or protecting group agent in peptide synthesis.
• Material Science Research: Utilized in developing novel organic frameworks and dendritic polymers.
• Fine Chemical Production: A versatile reagent for acylations and the preparation of esters and amides in complex molecule synthesis.

Basic Information

Product Name	1,2-Cyclohexanedicarbonyl Dichloride, trans-(+)- (9Ci)
CAS No.	33209-25-5
Molecular Formula	C8H10Cl2O2
Molecular Weight	209.07 g/mol
Synonyms	(1R,2R)-Cyclohexane-1,2-dicarbonyl dichloride; trans-(+)-1,2-Cyclohexanedicarboxylic Acid Dichloride; (1R,2R)-1,2-Cyclohexanedicarboxylic acid dichloride; (1R,2R)-1,2-Cyclohexanedicarbonyl chloride; trans-1,2-Cyclohexanedicarboxylic acid chloride; (R,R)-1,2-Cyclohexanedicarbonyl dichloride; (+)-trans-Cyclohexane-1,2-dicarbonyl dichloride; Cyclohexane-1,2-dicarboxylic acid dichloride, (1R,2R)-
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanedicarbonyl Dichloride, trans-(+)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and identity confirmation by IR and NMR spectroscopy, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive (hygroscopic) and reactive nature. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.