Description

Withanolide A(P) is a high-purity, naturally occurring steroidal lactone, a key bioactive constituent of the *Withania somnifera* (Ashwagandha) plant. Its significance lies in its potent and well-documented pharmacological activities, making it a critical reference standard and active ingredient for research and product development. This compound is essential for pharmaceutical, nutraceutical, and cosmeceutical industries focused on developing evidence-based health and wellness solutions.

Application

• Pharmaceutical Reference Standard: Used as a primary chemical standard for the quality control and standardization of Ashwagandha extracts and finished products in pharmacopoeial methods.
• Bioactivity & Mechanism Studies: Employed in preclinical and clinical research to investigate its anti-inflammatory, neuroprotective, adaptogenic, and anti-cancer properties.
• Nutraceutical Formulation: Serves as a marker compound for standardizing high-potency Ashwagandha dietary supplements to ensure consistent efficacy.
• Cosmeceutical Ingredients: Incorporated into advanced skincare formulations for its purported anti-aging and skin-soothing benefits.
• Herbal Drug Development: A crucial component in the development and validation of new herbal medicinal products.
• Academic & Institutional Research: Used in universities and research institutes for studying natural product chemistry and pharmacology.

Basic Information

Product Name	Withanolide A(P)
CAS No.	32911-62-9
Molecular Formula	C28H38O6
Molecular Weight	470.60 g/mol
Synonyms	Withanolide A; (22R)-5,6:22,26-Diepoxyergosta-2,24-diene-1,26-dione; Withaferin A analog; Ashwagandha lactone
EINECS	Contact for details

Quality Control

Our Withanolide A(P) is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Each batch is analyzed using advanced chromatographic techniques, including HPLC, against a certified reference standard. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.