Description

5-Methylaminomethyl-2-Thiouridine is a modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. Its unique thiolated and methylaminomethyl-modified structure makes it a valuable building block for studying RNA structure, function, and therapeutic targeting. This high-purity compound is essential for researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug discovery, and molecular biology.

Application

• Biochemical Research: A critical precursor for the synthesis of modified oligonucleotides to study RNA structure, stability, and protein interactions.
• Antiviral Drug Development: Serves as a key intermediate in the research and synthesis of novel nucleoside-based antiviral agents.
• Proteomics & Molecular Biology: Used in cross-linking studies and as a probe to investigate RNA-protein binding sites and mechanisms.
• Diagnostic Reagent Synthesis: Employed in the development of specialized nucleotides for diagnostic assays and sequencing technologies.
• Academic & Pharmaceutical R&D: A fundamental material for exploring novel therapeutic pathways involving RNA modification and gene expression regulation.

Basic Information

Product Name	5-Methylaminomethyl-2-Thiouridine
CAS No.	32860-54-1
Molecular Formula	C11H17N3O5S
Molecular Weight	303.34 g/mol
Synonyms	2-Thio-5-methylaminomethyluridine; 5-(Methylaminomethyl)-2-thiouridine; 5-MAM-2-SU; 2-Thiouridine, 5-(methylaminomethyl)-; 5-(Methylaminomethyl)-2-thio-1-β-D-ribofuranosyluracil; 5-Methylaminomethyl-2-thio-uridine; 5-MAMT; 2-Thio-5-(methylaminomethyl)uridine
EINECS	Contact for details

Quality Control

Our 5-Methylaminomethyl-2-Thiouridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.