Description

5'-Chloro-5'-Deoxyarabinosylcytosine is a chemically modified nucleoside analog, a key intermediate in the synthesis of more complex antiviral and anticancer pharmaceutical agents. Its value lies in its role as a versatile building block for developing novel therapeutic compounds, particularly in nucleotide-based drug discovery. This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers focused on oncology and antiviral R&D, as well as for fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced nucleoside-based antiviral and anticancer drugs.
• Antiviral Drug Research: Used in the development of novel therapeutic agents targeting viral replication mechanisms.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA synthesis in cancer cells.
• Biochemical Research: Employed in studies investigating nucleotide metabolism, enzyme inhibition, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Utilized in custom synthesis and the production of specialized nucleotide derivatives for various applications.

Basic Information

Product Name	5'-Chloro-5'-Deoxyarabinosylcytosine
CAS No.	32659-31-7
Molecular Formula	C9H12ClN3O4
Molecular Weight	261.66 g/mol
Synonyms	5'-Chloro-5'-deoxycytidine arabinoside; 5'-Chloro-ara-C; 2(1H)-Pyrimidinone, 4-amino-1-[(2R,3S,4S)-4-chloro-3,4-dihydro-2-(hydroxymethyl)-2H-pyran-3-yl]-; 4-Amino-1-[(2R,3S,4S)-4-chloro-3,4-dihydro-2-(hydroxymethyl)-2H-pyran-3-yl]-2(1H)-pyrimidinone; 5'-Chloro-5'-deoxy-1-β-D-arabinofuranosylcytosine; Cl-dAraC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5'-Chloro-5'-Deoxyarabinosylcytosine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and pharmaceutical synthesis. Products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.