Description

6-Quinolinecarbonyl Chloride, 1,2,3,4-Tetrahydro-1-Methyl- (8Ci) is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in its functionalized quinoline scaffold and acid chloride group, enabling efficient derivatization for the creation of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS) or possessing antimicrobial properties.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline moiety.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating complex nitrogen-containing ligands used in asymmetric catalysis and metal complexation.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, light-emitting materials, or advanced polymers with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	6-Quinolinecarbonyl Chloride, 1,2,3,4-Tetrahydro-1-Methyl- (8Ci)
CAS No.	32565-01-8
Molecular Formula	C12H12ClNO
Molecular Weight	221.68 g/mol
Synonyms	1-Methyl-1,2,3,4-tetrahydroquinoline-6-carbonyl chloride; 1-Methyl-6-quinolinecarbonyl chloride, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydro-1-methylquinoline-6-carbonyl chloride; 6-Carboxy-1-methyl-1,2,3,4-tetrahydroquinoline chloride; Tetrahydro-1-methyl-6-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Quinolinecarbonyl Chloride, 1,2,3,4-Tetrahydro-1-Methyl- (8Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.