Description

2-[2-(Furan-2-Ylmethylsulfanyl)-6-Hydroxy-Purin-9-Yl]-5-Hydroxymethyl-Tetrahydro-Furan-3,4-Diol is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for novel therapeutic agents, particularly in antiviral and anticancer applications. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and biotechnology companies engaged in the synthesis of modified nucleosides and nucleotide-based drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis pathways.
• Antiviral Drug Development: Investigated for its potential activity against a range of viral targets due to its modified purine structure.
• Oncology Research: Explored in the development of chemotherapeutic agents that interfere with cellular replication.
• Prodrug Synthesis: Utilized in creating prodrug forms to enhance the bioavailability and targeting of therapeutic nucleosides.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-[2-(Furan-2-Ylmethylsulfanyl)-6-Hydroxy-Purin-9-Yl]-5-Hydroxymethyl-Tetrahydro-Furan-3,4-Diol
CAS No.	32465-60-4
Molecular Formula	C15H16N4O6S
Molecular Weight	380.38 g/mol
Synonyms	6-Hydroxy-2-[(2-furanylmethyl)thio]-9H-purin-9-yl 5-(hydroxymethyl)oxolane-3,4-diol; 2-[(2-Furanylmethyl)thio]-6-hydroxy-9-[5-(hydroxymethyl)-3,4-dihydroxyoxolan-2-yl]purine; 6-Hydroxy-2-[(furan-2-ylmethyl)sulfanyl]purin-9-yl 5-(hydroxymethyl)oxolane-3,4-diol; Furan-2-ylmethylsulfanyl substituted purine nucleoside; Modified Thioguanosine Analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-[2-(Furan-2-Ylmethylsulfanyl)-6-Hydroxy-Purin-9-Yl]-5-Hydroxymethyl-Tetrahydro-Furan-3,4-Diol is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.