Description

5-Chloro-2'-Deoxycytidine is a halogenated nucleoside analog of deoxycytidine, a key building block in nucleic acid chemistry. This modified nucleoside is crucial for research and development in medicinal chemistry and molecular biology, serving as a versatile intermediate for synthesizing oligonucleotides and potential therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on antiviral drug discovery, cancer research, and the development of novel diagnostic probes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Oligonucleotide Synthesis: Used as a modified phosphoramidite building block for incorporating specific functionalities into DNA and RNA sequences.
• Biochemical Research: Employed in studies investigating DNA replication, repair mechanisms, and enzyme-substrate interactions.
• Antiviral Agent Development: Serves as a core scaffold for developing compounds targeting viral polymerases.
• Molecular Probe Synthesis: Utilized to create labeled nucleotides for diagnostic assays and genomic research.
• Chemical Biology Tool: Acts as a substrate for studying the activity and inhibition of various kinases and transferases.

Basic Information

Product Name	5-Chloro-2'-Deoxycytidine
CAS No.	32387-56-7
Molecular Formula	C9H12ClN3O4
Molecular Weight	261.66 g/mol
Synonyms	5-Chloro-2'-deoxycytidine; 5-Chloro-1-(2-deoxy-β-D-erythro-pentofuranosyl)cytosine; 5-Cl-dC; 5-Chlorodeoxycytidine; 2'-Deoxy-5-chlorocytidine; 5-Chloro-1-(2-deoxy-β-D-ribofuranosyl)cytosine; 5-Chloro-2'-deoxycytidine (5-CldC); 5-Chloro-2'-deoxycytidine, 5-Cl-dCyd
EINECS	Contact for details

Quality Control

Our 5-Chloro-2'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.