Description

2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Xylonic Acid δ-Lactone is a key protected sugar derivative and versatile chiral building block in advanced organic synthesis. Its primary value lies in its role as a crucial intermediate for the preparation of complex carbohydrates, nucleosides, and other biologically active molecules, offering controlled reactivity for selective functionalization. This high-purity specialty chemical is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science who require reliable, high-quality intermediates for their most demanding synthetic routes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry: Serves as a protected precursor for the controlled synthesis of oligosaccharides, glycoconjugates, and complex sugar derivatives.
• Agrochemical Research: Used in the development of new chiral herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the research and production of specialty polymers and functional materials with tailored properties.
• Process Chemistry & Scale-Up: Provides a reliable, high-purity starting point for process development and kilogram-to-ton scale manufacturing in fine chemical production.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and asymmetric catalysis studies.

Basic Information

Product Name	2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Xylonic Acid δ-Lactone
CAS No.	32384-59-1
Molecular Formula	C14H32O5Si3
Molecular Weight	364.66 g/mol
Synonyms	D-Xylonic acid, 2,3,4-tris-O-(trimethylsilyl)-, δ-lactone; 2,3,4-Tri-O-trimethylsilyl-D-xylono-1,5-lactone; Tris(trimethylsilyl) D-xylonolactone; TMS-protected D-xylonolactone; (3R,4S,5R)-3,4-Bis(trimethylsilyloxy)-5-[(trimethylsilyloxy)methyl]dihydrofuran-2(3H)-one; D-Xylono-1,5-lactone, 2,3,4-tris-O-(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our production of 2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Xylonic Acid δ-Lactone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.