Description

Gpcp (Gmpcp) CAS NO 32381-15-0 is a high-purity chemical intermediate of significant importance in advanced pharmaceutical synthesis and organic chemistry research. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of nucleoside analogs and other active pharmaceutical ingredients (APIs). This compound is essential for R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the production of antiviral, anticancer, and other specialty therapeutics. We supply this critical material with a focus on consistent quality, reliable purity, and secure global logistics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug development.
• Antiviral Pro-drug Synthesis: Used in the research and manufacturing of pro-drugs designed to improve the bioavailability and efficacy of antiviral agents.
• Organic Synthesis Reagent: Serves as a protected or activated monomer in complex multi-step organic syntheses, particularly in carbohydrate and heterocyclic chemistry.
• Biochemical Research: Employed in academic and industrial research settings for studying enzyme mechanisms, metabolic pathways, and as a precursor for labeled compounds.
• Fine Chemical Production: A critical raw material for contract manufacturing organizations (CMOs) and fine chemical suppliers producing custom intermediates for the life sciences industry.

Basic Information

Product Name	Gpcp (Gmpcp)
CAS No.	32381-15-0
Molecular Formula	C9H12N5O7P
Molecular Weight	333.20 g/mol
Synonyms	Guanosine 5'-(tetrahydrogen triphosphate), 2'-Deoxy-; 2'-Deoxyguanosine-5'-triphosphate; dGTP; Deoxyguanosine triphosphate; 2'-Deoxy-GTP; GMPCP; (2R,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl trihydrogen triphosphate
EINECS	Contact for details

Quality Control

Our Gpcp (Gmpcp) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request, ensuring compliance with stringent regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (HPLC, Anhydrous basis)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.