Description

Thyroxine Methyl Ester is a chemically modified derivative of the essential thyroid hormone, thyroxine (T4). This compound is a critical intermediate in pharmaceutical research and development, particularly for the synthesis of thyroid hormone analogs and diagnostic agents. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-purity intermediates for metabolic studies and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thyroid hormone analogs and potential therapeutic agents.
• Biochemical Research: Used in metabolic pathway studies, enzyme interaction assays, and endocrine system research.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Diagnostic Agent Development: Employed in the research and production of diagnostic kits and tracers for thyroid function testing.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental studies on hormone action and receptor binding.

Basic Information

Product Name	Thyroxine Methyl Ester
CAS No.	32180-11-3
Molecular Formula	C16H14I4NO4
Molecular Weight	821.01 g/mol
Synonyms	L-Thyroxine Methyl Ester; T4 Methyl Ester; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Methyl Ester; 3,3',5,5'-Tetraiodothyronine Methyl Ester; Levothyroxine Methyl Ester; Thyroxine Me ester; (2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Thyroxine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.