Description

10α-Pregna-5,7-Diene-3,20-Dione, Cyclic Bis(Ethylene Acetal) (8Ci) is a high-purity, specialized steroid derivative used as a critical synthetic intermediate. This compound matters for its precise molecular structure, which enables the development of novel pharmaceutical agents and advanced research materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for synthesizing complex molecules and exploring new therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Research & Development: Used in academic and industrial laboratories for studying steroid chemistry, reaction mechanisms, and developing new synthetic methodologies.
• Process Chemistry: Serves as a precursor in the scale-up and optimization of manufacturing routes for target molecules in pilot plants and commercial production.
• Biochemical Research: Employed in the study of enzyme inhibitors, receptor ligands, and other biologically active compounds due to its specific steroidal framework.
• Fine Chemical Synthesis: Utilized for the preparation of custom, high-value specialty chemicals with specific stereochemical and functional group requirements.

Basic Information

Product Name	10α-Pregna-5,7-Diene-3,20-Dione, Cyclic Bis(Ethylene Acetal) (8Ci)
CAS No.	32164-74-2
Molecular Formula	C27H38O4
Molecular Weight	426.59 g/mol
Synonyms	10α-Pregna-5,7-diene-3,20-dione cyclic bis(ethylene acetal); 5,7-Pregnadiene-3,20-dione, cyclic bis(ethylene acetal), 10α-; (8R,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,4,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,6-diyl di(ethylene acetal); Pregna-5,7-diene-3,20-dione cyclic bis(ethylene ketal); Steroid intermediate 32164-74-2.
EINECS	Contact for details

Quality Control

Our 10α-Pregna-5,7-Diene-3,20-Dione, Cyclic Bis(Ethylene Acetal) (8Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.