Description

17β-(Acetyloxy)-3β-Fluoroandrost-5-En-4-One CAS NO 31756-72-6 is a high-purity fluorinated steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in providing a structurally defined scaffold for the synthesis of novel therapeutic agents, enabling precise chemical modifications. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly those focused on endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new therapeutic molecules.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in studies investigating steroid metabolism, enzyme inhibition, and receptor binding assays.

Basic Information

Product Name	17β-(Acetyloxy)-3β-Fluoroandrost-5-En-4-One
CAS No.	31756-72-6
Molecular Formula	C21H29FO3
Molecular Weight	348.45 g/mol
Synonyms	3β-Fluoro-17β-acetoxyandrost-5-en-4-one; 3β-Fluoro-17β-hydroxyandrost-5-en-4-one 17-acetate; 4-Androsten-4-one-3β-fluoro-17β-ol, 17-acetate; 17β-Acetoxy-3β-fluoroandrost-5-en-4-one; Fluoxymesterone related compound; 3β-Fluoro-17β-acetoxy-5-androsten-4-one
EINECS	Contact for details

Quality Control

Our 17β-(Acetyloxy)-3β-Fluoroandrost-5-En-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.