Description

3β-Fluorocholest-4-En-6-One is a high-purity fluorinated steroidal ketone derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its unique structure, featuring a fluorine atom at the 3β position, makes it a valuable synthon for creating novel steroid-based drug candidates with modified biological activity and metabolic stability. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on developing new therapeutic agents targeting hormonal pathways, metabolic disorders, and other conditions influenced by steroidal frameworks.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel fluorinated steroid drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to explore the impact of fluorination on steroid pharmacology.
• Biochemical Research: Acts as a reference standard or probe in enzymatic studies involving steroid-metabolizing enzymes like cytochrome P450.
• Preclinical Studies: Utilized in the development and testing of new therapeutic candidates for oncology, endocrinology, and anti-inflammatory applications.
• Academic Research: Serves as a specialized chemical for universities and research institutes studying steroid chemistry and drug discovery.

Basic Information

Product Name	3β-Fluorocholest-4-En-6-One
CAS No.	31756-69-1
Molecular Formula	C27H43FO
Molecular Weight	402.63 g/mol
Synonyms	3β-Fluorocholest-4-en-6-one; 3-Fluorocholest-4-en-6-one; (3β)-Fluorocholest-4-en-6-one; 6-Cholesten-3β-fluoro-4-one; Cholest-4-en-6-one, 3-fluoro-, (3β)-; 3-Fluoro-5-cholesten-6-one; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3β-Fluorocholest-4-En-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.