Description

Bromhexine Hydrobromide is a synthetic derivative of vasicine, primarily recognized for its potent mucolytic activity. This high-purity active pharmaceutical ingredient (API) is essential for formulating effective respiratory therapeutics that address bronchial congestion. It is a critical raw material for pharmaceutical manufacturers producing cough suppressants and expectorants to treat conditions like chronic bronchitis and asthma. Our supply ensures the stringent quality and consistency required for global pharmaceutical production.

Application

• Pharmaceutical API: Primary use as the active ingredient in mucolytic and expectorant drug formulations.
• Tablet & Capsule Manufacturing: Direct compression or granulation for solid oral dosage forms.
• Syrup & Oral Solution Production: Solubilized for pediatric and geriatric liquid medications.
• Respiratory Disease Management: Key component in medications for chronic obstructive pulmonary disease (COPD), bronchitis, and asthma.
• Veterinary Pharmaceuticals: Used in veterinary cough preparations for animals.
• Research & Development: Serves as a reference standard and for developing novel drug delivery systems.

Basic Information

Product Name	Bromhexine Hydrobromide
CAS No.	31611-41-3
Molecular Formula	C₁₄H₂₀Br₂N₂
Molecular Weight	376.13 g/mol
Synonyms	Bromhexine HBr; 2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzenemethanamine hydrobromide; N-Cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrobromide; Bisolvon; Brovanexine; NA 274; Bromhexine hydrochloride (common misnomer); Bromhexinium bromide
EINECS	Contact for details

Quality Control

Our Bromhexine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmacopeial standards, including identification, purity, and impurity profiles. Certificates of Analysis (COA) documenting compliance with specifications such as USP, EP, or BP monographs are provided with every shipment to guarantee traceability and regulatory support for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.