Description

5-Bromothiophene-2-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. Its value lies in its role as a versatile building block for constructing complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is critically needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing thiophene or brominated heterocyclic cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific bromothiophene motifs.
• Material Science Research: Serves as a precursor for functional polymers, organic semiconductors, and liquid crystals.
• Chemical Research & Development: A crucial reagent for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.
• Dye & Pigment Industry: Intermediate for synthesizing specialized colorants and photographic chemicals.

Basic Information

Product Name	5-Bromothiophene-2-Carbonyl Chloride
CAS No.	31555-60-9
Molecular Formula	C5H2BrClOS
Molecular Weight	225.49 g/mol
Synonyms	2-Bromo-5-thiophenecarbonyl chloride; 5-Bromo-2-thiophenecarbonyl chloride; 5-Bromothiophene-2-carboxylic acid chloride; 2-Thiophenecarbonyl chloride, 5-bromo-; 5-Bromothiophene-2-carbonyl chloride; 5-Bromo-2-thienoyl chloride; 5-Bromothiophene-2-carboxyl chloride
EINECS	Contact for details

Quality Control

Our 5-Bromothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines. Due to its acid chloride nature and sensitivity to moisture, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.