Description

2,2'-Anhydro-L-Uridine is a specialized nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and building block for the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery. The material is supplied with a commitment to high purity and batch-to-batch consistency to support sensitive downstream applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of modified nucleosides and nucleotides for antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of novel therapeutic agents targeting RNA viruses, leveraging its modified uridine scaffold.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and related pathways.
• Prodrug Development: Serves as a building block for designing prodrugs with improved bioavailability and targeted delivery.
• Nucleic Acid Chemistry: Utilized in the synthesis of oligonucleotide analogs for diagnostic and therapeutic applications.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2,2'-Anhydro-L-Uridine
CAS No.	31501-46-9
Molecular Formula	C9H10N2O5
Molecular Weight	226.19 g/mol
Synonyms	2,2'-Anhydro-1-β-L-arabinofuranosyluracil; 2,2'-O-Cyclouridine, L-; L-2,2'-Anhydrouridine; 1-(β-L-Arabinofuranosyl)-2,2'-anhydrouracil; 2,2'-Anhydro-β-L-uridine; β-L-2,2'-Anhydrouridine; L-Anhydrouridine; 2,2'-Cyclouridine, L-Isomer
EINECS	Contact for details

Quality Control

Our 2,2'-Anhydro-L-Uridine is manufactured under strict quality management systems to ensure it meets the exacting requirements of pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP guidelines for non-clinical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.