Description

2'-Deoxy-L-Uridine is a stereoisomer of the fundamental nucleoside building block, deoxyuridine, distinguished by its L-configuration. This compound is of significant value in biochemical research and pharmaceutical development, particularly for studying nucleoside metabolism, enzyme specificity, and antiviral mechanisms. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and molecular biology applications. The product is supplied with a focus on high purity and batch-to-batch consistency to meet stringent research and development requirements.

Application

• Biochemical Research: Used as a substrate or reference standard in enzymatic studies, particularly for thymidylate synthase and other nucleoside-metabolizing enzymes.
• Antiviral Drug Development: Serves as a key intermediate or analog in the synthesis and evaluation of novel nucleoside-based antiviral agents.
• Diagnostic Reagent Manufacturing: Incorporated into kits and assays for the detection and quantification of enzymatic activity or nucleic acid metabolism.
• Metabolic Pathway Studies: Employed to investigate the salvage pathways of nucleoside metabolism in various biological systems.
• Pharmaceutical Intermediates: Acts as a chiral building block for the synthesis of more complex pharmaceutical compounds and prodrugs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemistry, biochemistry, and molecular biology.

Basic Information

Product Name	2'-Deoxy-L-Uridine
CAS No.	31501-19-6
Molecular Formula	C9H12N2O5
Molecular Weight	228.20 g/mol
Synonyms	L-2'-Deoxyuridine; (2S,3R,5S)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 1-((2S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; L-Deoxyuridine; β-L-2'-Deoxyuridine; Uridine, 2'-deoxy-, L-; 1-(2-Deoxy-β-L-erythro-pentofuranosyl)uracil
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-L-Uridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identification by IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. The product is suitable for research and development applications requiring high-purity biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.