Description

7,8-Dihydro-8-Oxoadenosine-3':5'-Cyclic Monophosphate is a chemically modified cyclic nucleotide derivative, structurally related to the fundamental second messenger cAMP. This compound matters as a valuable biochemical tool and a potential precursor in the development of nucleotide-based therapeutics and research probes. It is primarily needed by pharmaceutical R&D teams, academic researchers, and diagnostic manufacturers working in the fields of cell signaling, enzymology, and molecular biology.

Application

• Biochemical Research: Used as a stable analog or precursor in studies of cyclic nucleotide-dependent signaling pathways, protein kinases (PKA), and phosphodiesterases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis of novel nucleotide-based drugs targeting various cellular processes.
• Enzymology Studies: Employed as a substrate or inhibitor to investigate the activity and kinetics of enzymes that metabolize or bind cyclic nucleotides.
• Diagnostic Reagent Manufacturing: Utilized in the formulation of high-sensitivity assay kits for the detection and quantification of enzymatic activities or specific biomarkers.
• Cell Biology: Applied in cell culture experiments to modulate intracellular cAMP levels and study downstream effects on cell proliferation, differentiation, and gene expression.

Basic Information

Product Name	7,8-Dihydro-8-Oxoadenosine-3':5'-Cyclic Monophosphate
CAS No.	31356-95-3
Molecular Formula	C10H12N5O7P
Molecular Weight	345.21 g/mol
Synonyms	8-Oxo-cAMP; 8-Oxo-cyclic AMP; 7,8-Dihydro-8-oxoadenosine 3',5'-cyclic monophosphate; 8-Oxoadenosine 3',5'-cyclic phosphate; 8-Oxo-adenosine cyclic 3',5'-monophosphate; cAMP 8-oxo derivative; 31356-95-3
EINECS	Contact for details

Quality Control

Our 7,8-Dihydro-8-Oxoadenosine-3':5'-Cyclic Monophosphate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.