Description

8-Indoadenosine is a chemically modified nucleoside analog of adenosine, distinguished by the incorporation of an indole moiety. This structural modification is of significant interest for its potential to impart unique biochemical properties and enhance binding affinity in various research contexts. It serves as a valuable building block and research chemical for scientists in pharmaceutical discovery and life sciences, particularly in the development of novel therapeutic agents and as a tool for probing enzymatic mechanisms.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel nucleoside-based drug candidates targeting viral infections, cancer, and neurological disorders.
• Biochemical Tool Compound: Used in enzymatic studies to investigate the substrate specificity and inhibition of kinases, polymerases, and other adenosine-binding proteins.
• Probe Development: Serves as a precursor for fluorescent or affinity-labeled probes to study nucleic acid interactions and cellular processes.
• Academic Research: Employed in universities and research institutes for fundamental studies in medicinal chemistry and chemical biology.
• Process Chemistry: Utilized in scaling up synthetic routes for advanced pharmaceutical intermediates under GMP or non-GMP conditions.

Basic Information

Product Name	8-Indoadenosine
CAS No.	31281-88-6
Molecular Formula	C18H18N6O4
Molecular Weight	382.38 g/mol
Synonyms	8-(1H-Indol-3-yl)adenosine; 8-(3-Indolyl)adenosine; Adenosine, 8-(1H-indol-3-yl)-; 8-Indol-3-yl-adenosine; N6-(1H-Indol-3-yl)adenosine (isomer); Research Grade 8-Indoadenosine; 8-IA
EINECS	Contact for details

Quality Control

Every batch of our 8-Indoadenosine is manufactured and tested under a strict quality management system to ensure high purity, consistency, and traceability. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom synthesis to meet specific pharmacopeial (USP/EP) or internal specifications is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.