Description

1,1'-Biphenyl, 4-(Isothiocyanatomethyl)- is a specialized organic compound featuring a biphenyl core functionalized with an isothiocyanatomethyl group. This unique structure makes it a valuable intermediate and reagent in advanced chemical synthesis, particularly for creating complex molecules with specific biological or material properties. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific biological pathways.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and plant growth regulators.
• Ligand and Conjugate Synthesis: The reactive isothiocyanate group is utilized for coupling to amines, making it useful for creating fluorescent probes, bioconjugates, and chelating agents.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers and liquid crystals.
• Chemical Biology: Employed in activity-based protein profiling (ABPP) and other proteomic studies to label and study enzymes.
• Organic Synthesis Reagent: A versatile reagent for introducing the biphenyl-isothiocyanate moiety into more complex molecular architectures.

Basic Information

Product Name	1,1'-Biphenyl, 4-(Isothiocyanatomethyl)-
CAS No.	31162-25-1
Molecular Formula	C14H11NS
Molecular Weight	225.31 g/mol
Synonyms	4-(Isothiocyanatomethyl)biphenyl; [1,1'-Biphenyl]-4-methyl isothiocyanate; p-(Isothiocyanatomethyl)biphenyl; 4-Methylbiphenyl isothiocyanate; Biphenyl-4-methyl isothiocyanate; 4-Biphenylmethyl isothiocyanate; NSC 403119; 4-(Biphenyl-4-ylmethyl)isothiocyanate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques such as HPLC, GC, and NMR to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to strict quality management protocols to guarantee the reliability required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.