Description

4-Methoxycarbonylphenyl Chloroformate is a versatile and highly reactive chloroformate ester, widely used as a key building block in organic synthesis. Its primary value lies in its ability to act as a protecting group or coupling agent for carboxylic acids and amines, facilitating the synthesis of complex molecules. This intermediate is particularly critical for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity reagents for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating amide bonds and carbonate linkages.
• Peptide Synthesis: Used as a coupling agent or protecting group in solid-phase and solution-phase peptide chemistry.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for the production of specialty polycarbonates and polyurethanes.
• Agrochemical Synthesis: Employed in the manufacture of herbicides, fungicides, and insecticides where specific carbonate or carbamate functionalities are required.
• Material Science: Used in surface modification and the creation of functionalized materials with tailored properties.
• Bioconjugation: Facilitates the attachment of drugs, dyes, or other molecules to proteins, antibodies, or polymers for diagnostic and therapeutic applications.

Basic Information

Product Name	4-Methoxycarbonylphenyl Chloroformate
CAS No.	31140-40-6
Molecular Formula	C9H7ClO4
Molecular Weight	214.60 g/mol
Synonyms	Methyl 4-(Chloroformyloxy)benzoate; p-(Methoxycarbonyl)phenyl Chloroformate; 4-(Chloroformyloxy)benzoic Acid Methyl Ester; Methyl 4-Hydroxybenzoate Chloroformate; Carbonochloridic Acid, 4-(Methoxycarbonyl)phenyl Ester; p-Carbomethoxyphenyl Chloroformate
EINECS	Contact for details

Quality Control

Our 4-Methoxycarbonylphenyl Chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.