Description

2(1H)-Pyrimidinone, 4-Amino-1-[5-o-(2-Methyl-1-Oxopropyl)-β-D-Arabinofuranosyl]- is a sophisticated nucleoside analog with significant pharmaceutical research and development value. This compound is a key synthetic intermediate in the production of antiviral and anticancer agents, offering a critical building block for advanced medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutics targeting viral infections and oncology.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the R&D of compounds targeting DNA and RNA viruses.
• Oncology Research: Serves as a building block for developing chemotherapeutic agents that interfere with nucleic acid synthesis.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate metabolic pathways.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	2(1H)-Pyrimidinone, 4-Amino-1-[5-o-(2-Methyl-1-Oxopropyl)-β-D-Arabinofuranosyl]-
CAS No.	31088-20-7
Molecular Formula	C13H19N3O6
Molecular Weight	313.31 g/mol
Synonyms	4-Amino-1-(5-O-isobutyryl-β-D-arabinofuranosyl)-2(1H)-pyrimidinone; 4-Amino-1-(5-O-(2-methylpropanoyl)-β-D-arabinofuranosyl)pyrimidin-2(1H)-one; 4-Amino-1-(5-O-isobutyryl-β-D-arabinofuranosyl)uracil; 4-Amino-1-(5-O-isobutyryl-β-D-arabinofuranosyl)-2(1H)-pyrimidinone; Isobutyryl Prodrug of Arabinosylcytosine (Intermediate); Ara-C Isobutyrate Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.