Description

[2-[(Trimethylsilyl)Oxy]Trimethylenebis(Oxy)]Bis[Phosphonic Acid Bis(Trimethylsilyl)] Ester is a specialized organosilicon-protected phosphonate derivative, valued for its role as a key synthetic intermediate and protecting group reagent. Its primary commercial value lies in enabling precise chemical transformations in sensitive synthesis, particularly for introducing phosphonate functionalities under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reactive intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphonate or bisphosphonate groups for therapeutic applications.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, plant growth regulators, and other crop protection agents with tailored properties.
• Ligand and Catalyst Preparation: Employed in the development of specialized phosphonate-based ligands for metal catalysis and coordination chemistry.
• Surface Modification Agent: Utilized to functionalize material surfaces (e.g., silica, metals) with stable phosphonate layers for improved adhesion, corrosion resistance, or biocompatibility.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with flame-retardant or metal-chelating characteristics.
• Chemical Research & Development: A critical reagent in organic synthesis laboratories for constructing complex molecular architectures, leveraging the trimethylsilyl groups for temporary protection of reactive sites.

Basic Information

Product Name	[2-[(Trimethylsilyl)Oxy]Trimethylenebis(Oxy)]Bis[Phosphonic Acid Bis(Trimethylsilyl)] Ester
CAS No.	31038-36-5
Molecular Formula	C18H48O8P2Si5
Molecular Weight	594.99 g/mol
Synonyms	Bis(trimethylsilyl) [2-[(trimethylsilyl)oxy]trimethylenebis(oxy)]bisphosphonate; Phosphonic acid, P,P'-[2-[(trimethylsilyl)oxy]-1,3-propanediyl] P,P,P',P'-tetrakis(trimethylsilyl) ester; Tetrakis(trimethylsilyl) 2-[(trimethylsilyl)oxy]-1,3-propanediylbis(phosphonate); TMS-Protected Propylene Glycol Bisphosphonate Ester; 1,3-Bis[bis(trimethylsilyl)phosphonato]-2-(trimethylsilyloxy)propane; Silylated Bisphosphonate Ester; CAS 31038-36-5
EINECS	Contact for details

Quality Control

Our production of [2-[(Trimethylsilyl)Oxy]Trimethylenebis(Oxy)]Bis[Phosphonic Acid Bis(Trimethylsilyl)] Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is analyzed using advanced techniques including NMR (¹H, ¹³C, ³¹P), GC, and HPLC to verify identity and purity. Comprehensive Certificates of Analysis (COA) detailing all specification parameters are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.