Description

Adenosine, N,n-Dimethyl-2'-o-Methyl- CAS NO 30891-53-3 is a chemically modified nucleoside analog, specifically a dimethylated and O-methylated derivative of adenosine. This structural modification is critical for enhancing metabolic stability and modulating biological activity, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of oncology, virology, and cardiovascular disease.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside-based drugs and prodrugs.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies and metabolic pathway analysis.
• Antiviral Drug Development: Serves as a precursor in the research of antiviral compounds targeting viral polymerases.
• Oncology Research: Investigated for its potential role in developing chemotherapeutic agents that interfere with nucleotide metabolism in cancer cells.
• Enzyme Inhibitor Studies: Employed to study the structure-activity relationships of adenosine receptor ligands and kinase inhibitors.
• Labeled Compound Synthesis: Acts as a starting material for the preparation of isotopically labeled (e.g., C13, N15) analogs for tracer studies.

Basic Information

Product Name	Adenosine, N,n-Dimethyl-2'-o-Methyl-
CAS No.	30891-53-3
Molecular Formula	C₁₂H₁₇N₅O₄
Molecular Weight	295.30 g/mol
Synonyms	2'-O-Methyl-N6,N6-dimethyladenosine; N6,N6-Dimethyl-2'-O-methyladenosine; 1-(2-O-Methyl-β-D-ribofuranosyl)-N6,N6-dimethyladenine; 2'-O-Methyl-N6-dimethyladenosine; N6,N6-Dimethyl-2'-O-methyl-9-β-D-ribofuranosyladenine; 30891-53-3; Adenosine, N6,N6-dimethyl-2'-O-methyl-
EINECS	Contact for details

Quality Control

Our Adenosine, N,n-Dimethyl-2'-o-Methyl- is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet general research-grade standards, specifications can be aligned with specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.