Description

1,2,5-Thiadiazole-3-Carbonyl Chloride (9Ci) is a versatile and highly reactive heterocyclic building block, primarily used as a key intermediate in the synthesis of complex organic molecules. Its core value lies in its ability to efficiently introduce the 1,2,5-thiadiazole moiety, a privileged scaffold known for imparting significant biological activity and unique electronic properties to target compounds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiadiazole ring.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as semiconductors and light-emitting components.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	1,2,5-Thiadiazole-3-Carbonyl Chloride (9Ci)
CAS No.	30853-22-6
Molecular Formula	C3ClN2OS
Molecular Weight	148.55 g/mol
Synonyms	1,2,5-Thiadiazole-3-carbonyl chloride; 1,2,5-Thiadiazole-3-carboxylic acid chloride; 3-Chlorocarbonyl-1,2,5-thiadiazole; 1,2,5-Thiadiazole-3-carbonyl chloride (9CI); Thiadiazole-3-carbonyl chloride; 1,2,5-Thiadiazole-3-Carboxylic Acid Chloride; 1,2,5-Thiadiazole-3-Carboxychloride
EINECS	Contact for details

Quality Control

Our 1,2,5-Thiadiazole-3-Carbonyl Chloride is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and stored at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.