Description

n-Acetyl-L-Thyroxine Ethyl Ester is a chemically modified derivative of the thyroid hormone thyroxine, designed for enhanced stability and specific reactivity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel thyroid hormone analogs and diagnostic agents. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular control.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of thyroid hormone derivatives and potential therapeutic agents.
• Biochemical Research: Used in metabolic studies, receptor binding assays, and investigations into thyroid hormone action and regulation.
• Diagnostic Agent Development: Serves as a starting material for creating labeled compounds used in diagnostic tests and imaging.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control of related compounds.
• Peptide & Protein Modification: Utilized in research exploring chemical modifications of biomolecules to study structure-function relationships.

Basic Information

Product Name	n-Acetyl-L-Thyroxine Ethyl Ester
CAS No.	30804-52-5
Molecular Formula	C17H17I4NO6
Molecular Weight	862.94 g/mol
Synonyms	O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine N-Acetyl Ethyl Ester; L-Thyroxine, N-acetyl-, ethyl ester; Acetylthyroxine Ethyl Ester; Ethyl N-Acetyl-L-thyroxinate; Thyroxine Acetyl Ethyl Ester; N-Acetyl-L-thyroxine ethyl ester; N-Acetylthyroxine Ethyl Ester
EINECS	Contact for details

Quality Control

Our n-Acetyl-L-Thyroxine Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.