Description

5-Methoxy-2-Thiouridine is a modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool for studying RNA structure, function, and therapeutic modulation. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and molecular biology. The high-purity material enables precise investigations into nucleic acid interactions and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Essential tool for studying RNA modification, structure, and function in molecular biology.
• Antiviral Drug Development: Investigated for incorporation into oligonucleotides targeting viral RNA.
• Proteomics & Genomics: Used in cross-linking studies and as a probe for nucleic acid-protein interactions.
• Academic Research: Fundamental compound for universities and institutes exploring nucleotide chemistry and metabolism.
• Diagnostic Reagent Synthesis: Potential component in the development of specialized diagnostic assays and probes.

Basic Information

Product Name	5-Methoxy-2-Thiouridine
CAS No.	30771-43-8
Molecular Formula	C10H14N2O6S
Molecular Weight	290.29 g/mol
Synonyms	5-Methoxy-2-thiouridine; 2-Thio-5-methoxyuridine; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxy-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one; 5-Methoxy-2-thio-uridine; 2-Thiouridine, 5-methoxy-; 5-Methoxy-2-thiouridine (CAS 30771-43-8)
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-Thiouridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support research and development with material that meets the stringent requirements for pharmaceutical intermediate and biochemical reagent use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.