Description

8-Aminoadenosine 3':5'-Cyclicmonophospha Te Free Ac is a chemically modified derivative of cyclic adenosine monophosphate (cAMP), a fundamental secondary messenger in cellular signaling. This compound is of significant interest for biochemical research due to its role as a stable, cell-permeable analog that can modulate protein kinase A (PKA) activity. It is primarily utilized by researchers in pharmaceutical development, molecular biology, and signal transduction studies to investigate intracellular pathways and develop novel therapeutic strategies.

Application

• Biochemical Research: As a key tool compound for studying cAMP-dependent protein kinase (PKA) signaling pathways and cellular response mechanisms.
• Pharmaceutical R&D: Used in high-throughput screening and target validation for diseases where cAMP signaling is dysregulated, such as cardiac disorders and certain cancers.
• Cell Biology Studies: Employed to investigate the effects of sustained cAMP elevation on cell proliferation, differentiation, and apoptosis in various cell lines.
• Enzyme Inhibition/Activation Studies: Serves as a substrate or modulator in assays for phosphodiesterases (PDEs) and other enzymes involved in nucleotide metabolism.
• Neuroscience Research: Applied in studies of synaptic plasticity, memory formation, and neurotransmitter release where cAMP is a critical mediator.
• Reference Standard: Used as an analytical standard in HPLC, LC-MS, or NMR for quality control and method development in analytical laboratories.

Basic Information

Product Name	8-Aminoadenosine 3':5'-Cyclicmonophospha Te Free Ac
CAS No.	30685-40-6
Molecular Formula	C₁₅H₁₈N₇O₇P
Molecular Weight	463.32 g/mol
Synonyms	8-Aminoadenosine 3',5'-cyclic monophosphate; 8-NH2-cAMP; 8-Amino-cAMP; 8-Aminocyclic AMP; 8-Aminoadenosine cyclic 3',5'-phosphate; Adenosine, 8-amino-3',5'-cyclic monophosphate; 8-Amino-cyclic adenosine monophosphate
EINECS	Contact for details

Quality Control

Our 8-Aminoadenosine 3':5'-Cyclicmonophospha Te Free Ac is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, NMR confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.