Description

(3A,5B,7A,12A)-Cholestane-3,7,12,23-Tetrol is a high-purity, multi-hydroxylated sterol derivative, serving as a critical intermediate and reference standard in advanced biochemical research and pharmaceutical development. Its precise stereochemistry and functional group array make it invaluable for studying bile acid biosynthesis, metabolic pathways, and as a building block for synthesizing complex steroid-based compounds. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require well-characterized, high-quality sterol intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel steroid-based therapeutics and bile acid analogs.
• Biochemical Research: Reference standard and probe for investigating enzymatic pathways involved in cholesterol and bile acid metabolism.
• Metabolic Studies: Used in in vitro and in vivo studies to elucidate the biological roles of hydroxylated sterols and their derivatives.
• Fine Chemical Synthesis: A versatile chiral building block for the asymmetric synthesis of complex natural products and specialty chemicals.
• Analytical Standard: High-purity material for use as a calibration standard in chromatographic (HPLC, GC) and spectroscopic analyses.

Basic Information

Product Name	(3A,5B,7A,12A)-Cholestane-3,7,12,23-Tetrol
CAS No.	30673-09-7
Molecular Formula	C₂₇H₄₈O₄
Molecular Weight	436.67 g/mol
Synonyms	23-Hydroxycholic Acid; 3α,7α,12α,23-Tetrahydroxy-5β-cholestane; 5β-Cholestane-3α,7α,12α,23-tetrol; Cholestane-3,7,12,23-tetrol, (3α,5β,7α,12α)-; 23-Hydroxy-5β-cholestane-3α,7α,12α-triol
EINECS	Contact for details

Quality Control

Our (3A,5B,7A,12A)-Cholestane-3,7,12,23-Tetrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.