Description

(22R)-2β,3β,20,22,25-Pentahydroxy-5β-Cholesta-7,14-Dien-6-One is a highly functionalized cholestane derivative, a key intermediate in the synthesis of complex steroidal compounds. Its multi-hydroxylated structure makes it a valuable scaffold for pharmaceutical research and development, particularly in exploring novel bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in steroid chemistry, drug discovery, and the synthesis of specialized biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or reference standard in metabolic pathway studies and enzyme inhibition assays related to sterol biosynthesis.
• Drug Discovery: Acts as a versatile scaffold for medicinal chemists to develop new chemical entities targeting hormone receptors or metabolic enzymes.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control of steroidal compounds using HPLC or LC-MS.
• Academic Research: Utilized in university and institutional labs for studying organic synthesis methodologies, particularly oxidation and hydroxylation reactions on steroidal backbones.

Basic Information

Product Name	(22R)-2β,3β,20,22,25-Pentahydroxy-5β-Cholesta-7,14-Dien-6-One
CAS No.	30655-79-9
Molecular Formula	C₂₇H₄₂O₆
Molecular Weight	462.62 g/mol
Synonyms	2β,3β,20,22,25-Pentahydroxycholesta-7,14-dien-6-one; (22R)-Cholesta-7,14-diene-2,3,20,22,25-pentol, 6-one; 5β-Cholesta-7,14-diene-2β,3β,20,22,25-pentol-6-one; 22R-Pentahydroxycholestadienone; Steroid intermediate 30655-79-9; 2,3,20,22,25-Pentahydroxy-5β-cholesta-7,14-dien-6-one
EINECS	Contact for details

Quality Control

Every batch of (22R)-2β,3β,20,22,25-Pentahydroxy-5β-Cholesta-7,14-Dien-6-One is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, purity by HPLC, and identification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.