Description

(3Beta,5Beta,11Alpha)-3-[(7-Carboxy-1-Oxoheptyl)Oxy]-11,14-Dihydroxy-12-Oxo-Bufa-20,22-Dienolide is a high-purity, structurally defined bufadienolide derivative, a class of compounds known for their potent biological activity. This compound is critical for pharmaceutical research and development, serving as a key reference standard and a sophisticated synthetic intermediate. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in the fields of cardiology and oncology.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of bufadienolide compounds in research and quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a crucial building block in the multi-step synthesis of complex, biologically active drug candidates.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) and mechanisms of action related to Na+/K+-ATPase inhibition.
• Preclinical Development: Utilized in the formulation and testing of new chemical entities (NCEs) during early-stage drug discovery programs.
• Academic Research: Supports university and institutional research into natural product derivatives and their potential therapeutic applications.

Basic Information

Item	Detail
Product Name	(3Beta,5Beta,11Alpha)-3-[(7-Carboxy-1-Oxoheptyl)Oxy]-11,14-Dihydroxy-12-Oxo-Bufa-20,22-Dienolide
CAS No.	30219-16-0
Molecular Formula	C32H42O10
Molecular Weight	586.68 g/mol
Synonyms	3β-[(7-Carboxy-1-oxoheptyl)oxy]-11α,14-dihydroxy-12-oxobufa-20,22-dienolide; 3β-[(7-Carboxy-1-oxoheptyl)oxy]-11α,14-dihydroxy-12-oxobufa-20,22-dienolide; 11α,14-Dihydroxy-3β-[(7-carboxy-1-oxoheptyl)oxy]-12-oxobufa-20,22-dienolide; Bufadienolide derivative; Bufalin derivative; 30219-16-0; (3β,5β,11α)-3-[(7-Carboxy-1-oxoheptyl)oxy]-11,14-dihydroxy-12-oxobufa-20,22-dienolide
EINECS	Contact for details

Quality Control

Our (3Beta,5Beta,11Alpha)-3-[(7-Carboxy-1-Oxoheptyl)Oxy]-11,14-Dihydroxy-12-Oxo-Bufa-20,22-Dienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting standards for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic and should be handled under an inert atmosphere when possible to prevent moisture absorption and degradation. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.