Description

1,3-Thiazole-2-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. Its primary value lies in its role as a versatile acylating and building block agent for constructing complex heterocyclic molecules. This compound is critically needed by research and development chemists, as well as production-scale manufacturers, in the pharmaceutical and agrochemical industries to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with thiazole-based pharmacophores for antiviral, antibacterial, or anticancer activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the thiazole moiety imparts specific biological activity.
• Material Science Research: Serves as a precursor for functional polymers, liquid crystals, or organic electronic materials requiring specific heterocyclic units.
• Chemical Derivatization: Employed as an acyl chloride reagent to introduce the 1,3-thiazole-2-carbonyl group into other molecules for structure-activity relationship (SAR) studies.
• Peptide Mimetics & Bioconjugation: Facilitates the creation of peptide analogs or the labeling of biomolecules for diagnostic or therapeutic applications.

Basic Information

Product Name	1,3-Thiazole-2-Carbonyl Chloride
CAS No.	30216-57-0
Molecular Formula	C4H2ClNOS
Molecular Weight	147.58 g/mol
Synonyms	2-Thiazolecarbonyl chloride; Thiazole-2-carbonyl chloride; 2-Carbonylchloridethiazole; 1,3-Thiazole-2-carboxylic acid chloride; 2-Thiazolylcarbonyl chloride; 2-Thiazolecarboxylic acid chloride; T2CC; 2-Thiazole carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1,3-Thiazole-2-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and meet stringent impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.