Description

1H-Benzimidazole-2-Carbonylchloride(9Ci) is a versatile and reactive organic intermediate belonging to the benzimidazole class. This compound is a critical building block in the synthesis of more complex molecules, valued for its ability to introduce the benzimidazole pharmacophore and serve as an acyl chloride coupling agent. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting viral, fungal, and parasitic infections.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic materials.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling proteins, peptides, and other biomolecules due to its reactive carbonyl chloride group.
• Ligand Synthesis for Catalysis: Building block for creating N-heterocyclic carbene (NHC) precursors and other specialized ligands used in catalytic systems.

Basic Information

Product Name	1H-Benzimidazole-2-Carbonylchloride(9Ci)
CAS No.	30183-14-3
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	2-Benzimidazolecarbonyl chloride; 1H-Benzimidazole-2-carbonyl chloride; 2-Carboxybenzimidazole chloride; Benzimidazole-2-carbonyl chloride; 2-(Chlorocarbonyl)-1H-benzimidazole; NSC 163063; 2-Benzimidazolyl carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazole-2-Carbonylchloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.