Description

5,6-Dihydro-Ara-Uridine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a key intermediate or reference standard in the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleic acid metabolism. It is primarily utilized by research institutions, pharmaceutical companies, and CROs engaged in nucleoside chemistry, medicinal chemistry, and biochemical studies. The high-purity material is essential for ensuring the accuracy and reproducibility of experimental results in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of advanced nucleoside-based therapeutics.
• Antiviral Drug Research: Used in the development and study of potential antiviral compounds targeting viral polymerases.
• Oncology Research: Serves as a precursor or analog in the investigation of antimetabolite chemotherapeutic agents.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical labs.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Product Name	5,6-Dihydro-Ara-Uridine
CAS No.	30100-83-5
Molecular Formula	C9H12N2O6
Molecular Weight	244.20 g/mol
Synonyms	5,6-Dihydro-1-β-D-arabinofuranosyluracil; 1-(β-D-Arabinofuranosyl)-5,6-dihydrouracil; Dihydroarauridine; Ara-DHU; 5,6-Dihydrouridine arabinoside; 1-(β-D-Arabinofuranosyl)dihydrouracil; 5,6-Dihydro-araU
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-Ara-Uridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material integrity for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.