Description

22-Azacholesterol is a synthetic azasteroid derivative, a key intermediate in the research and development of novel pharmaceutical compounds. This compound is valued for its role in modulating sterol metabolism and as a building block for creating potential therapeutic agents targeting cholesterol-related pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, biochemistry, and the development of enzyme inhibitors.

Application

• Medicinal Chemistry Research: Serves as a crucial intermediate in the synthesis of novel azasteroid-based drug candidates for investigating cholesterol biosynthesis and metabolism.
• Biochemical Studies: Used as a tool compound in enzymatic assays to study the inhibition of sterol-metabolizing enzymes like sterol reductases or demethylases.
• Pharmaceutical Development: Acts as a precursor in the development of potential therapeutic agents for conditions related to lipid disorders and hormonal regulation.
• Academic Research: Employed in university and institutional labs for fundamental studies on steroid analog synthesis and their biological activity profiles.
• Reference Standard: Can be used as an analytical standard in chromatographic methods (HPLC, GC) for quality control and method development in related synthetic processes.

Basic Information

Product Name	22-Azacholesterol
CAS No.	3915-24-0
Molecular Formula	C27H47N
Molecular Weight	385.67 g/mol
Synonyms	22-Aza-5-cholesten-3β-ol; 22-Azacholest-5-en-3β-ol; 3β-Hydroxy-22-azacholest-5-ene; 22-Azacholest-5-en-3-ol; NSC 89267; 22-Aza-cholesterol; Azacholesterol derivative; 22-Norcholest-5-en-3β-ol-22-amine
EINECS	Contact for details

Quality Control

Our 22-Azacholesterol is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.