Description

Trioxsalen is a synthetic psoralen derivative, a key active pharmaceutical ingredient (API) in photochemotherapy. This compound is specifically engineered to increase the skin's sensitivity to ultraviolet A (UVA) light, enabling targeted therapeutic effects. It is primarily utilized by pharmaceutical manufacturers and research institutions developing treatments for dermatological conditions such as vitiligo and psoriasis, as well as in photopheresis procedures.

Application

• Photochemotherapy (PUVA) for Vitiligo: A core component in repigmentation therapy protocols, used in conjunction with controlled UVA light exposure.
• Psoriasis Treatment: Employed in systemic or topical PUVA therapy to slow the rapid growth of skin cells.
• Extracorporeal Photopheresis (ECP): Used in the treatment of cutaneous T-cell lymphoma (CTCL) and graft-versus-host disease (GvHD).
• Dermatological Research: Serves as a critical reference standard and active compound in studies of photobiology and skin disorders.
• Pharmaceutical Intermediates: Acts as a starting material or intermediate in the synthesis of more complex therapeutic agents.
• Analytical Reference Standard: Used in quality control laboratories for HPLC, GC, or other analytical method development and validation.

Basic Information

Product Name	Trioxsalen
CAS No.	3902-71-4
Molecular Formula	C14H12O3
Molecular Weight	228.24 g/mol
Synonyms	Trioxysalen; 4,5',8-Trimethylpsoralen; Trisoralen; TMP; 2,5,9-Trimethyl-7H-furo[3,2-g]chromen-7-one; 4,5',8-Trimethylpsoralene
EINECS	223-463-4

Quality Control

Our Trioxsalen is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.