Description

Cucurbitacin D is a highly oxygenated tetracyclic triterpenoid belonging to the cucurbitacin family of natural products. This compound is valued for its potent biological activity, serving as a critical reference standard and a promising lead compound in pharmacological research. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors for its role in studying cell signaling pathways and developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of anti-cancer and anti-inflammatory therapeutics.
• Biochemical Research: Employed as a potent and selective inhibitor of the JAK/STAT signaling pathway for studying cell proliferation, apoptosis, and immune responses.
• Natural Product Isolation & Analysis: Serves as a key analytical standard for the identification and quantification of cucurbitacins in plant extracts and herbal formulations.
• Academic & Institutional Research: Utilized in university and contract research organization (CRO) laboratories for investigating the mechanisms of triterpenoid bioactivity.
• Preclinical Studies: Applied in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and toxicology profiles.
• Quality Control & Standardization: Acts as a certified reference material (CRM) for ensuring the consistency and potency of botanical dietary supplements containing cucurbitacin-producing plants.

Basic Information

Item	Detail
Product Name	Cucurbitacin D
CAS No.	3877-86-9
Molecular Formula	C₃₀H₄₄O₇
Molecular Weight	516.67 g/mol
Synonyms	Elatericin A; 23,24-Dihydrocucurbitacin F; 23,24-Dihydro-10α-cucurbitacin F; (23S)-23,24-Dihydrocucurbitacin F; Cuc D; NSC 106399; 3β,16α,20(R),25-Tetrahydroxy-9-methyl-19-norlanosta-5,23-diene-11,22-dione
EINECS	Contact for details

Quality Control

Our Cucurbitacin D is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.