Description

1-(2,5-Difluorophenyl)Ethanol is a versatile fluorinated aromatic alcohol building block. This compound is valued for its role as a key chiral intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced materials, and specialty chemicals where the introduction of a fluorinated phenyl ethanol moiety is required. The product is supplied to meet the stringent quality demands of industrial-scale synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the production of active pharmaceutical ingredients (APIs), especially in drug discovery and development programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the difluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display materials and organic light-emitting diodes (OLEDs).
• Specialty Polymer Modifier: Incorporated to impart specific properties like chemical resistance or altered solubility in high-performance polymers and resins.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, asymmetric synthesis, and as a starting material for various fluorinated fine chemicals in research and development.

Basic Information

Product Name	1-(2,5-Difluorophenyl)Ethanol
CAS No.	3874-31-5
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	2,5-Difluoro-α-methylbenzyl Alcohol; (2,5-Difluorophenyl)methylcarbinol; α-Methyl-2,5-difluorobenzyl Alcohol; 1-(2,5-Difluorophenyl)ethan-1-ol; 2,5-Difluoro-α-phenethyl Alcohol; 1-(2,5-Difluorophenyl)ethyl Alcohol; (RS)-1-(2,5-Difluorophenyl)ethanol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and impurity profile. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and assurance for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.