Description

8-Benzyloxyguanosine is a key nucleoside derivative, specifically a protected guanosine analog, widely utilized in pharmaceutical research and synthesis. This compound is essential for the development of antiviral and anticancer agents, serving as a critical building block in nucleoside chemistry. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of modified oligonucleotides and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies involving DNA/RNA modification, enzyme inhibition, and cellular signaling pathways.
• Oligonucleotide Synthesis: Serves as a protected monomer for the solid-phase synthesis of modified oligonucleotides for diagnostic and therapeutic applications.
• Prodrug Development: Employed in the design and synthesis of prodrugs to enhance the bioavailability and targeting of nucleoside-based therapeutics.
• Chemical Biology Probes: Utilized to create labeled or tagged nucleosides for tracking metabolic incorporation and studying biological processes.
• Academic & Industrial R&D: Fundamental reagent in organic and medicinal chemistry laboratories for exploring new chemical entities.

Basic Information

Product Name	8-Benzyloxyguanosine
CAS No.	3868-36-8
Molecular Formula	C₁₇H₁₉N₅O₆
Molecular Weight	389.36 g/mol
Synonyms	8-O-Benzylguanosine; Guanosine, 8-(phenylmethoxy)-; 8-(Benzyloxy)guanosine; 8-Benzyloxy-9H-purin-6-amine, 9-β-D-ribofuranosyl-; NSC 154042; 8-O-Benzyl-guanosine
EINECS	Contact for details

Quality Control

Our 8-Benzyloxyguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.