Description

(-)-β-Narcotine CAS NO 3860-46-6 is a high-purity, optically active alkaloid compound of significant interest in advanced chemical synthesis and research. This specific enantiomer is valued for its role as a critical chiral building block and reference standard in pharmaceutical development and analytical chemistry. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex molecules, drug discovery programs, and method validation.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of specialized active pharmaceutical ingredients (APIs) and novel drug candidates.
• Analytical Reference Standard: Used for method development, calibration, and quality control in HPLC, GC, and LC-MS analyses within pharmaceutical and forensic laboratories.
• Biochemical Research: Employed in pharmacological studies to investigate receptor interactions, metabolic pathways, and the biological activity of alkaloid derivatives.
• Asymmetric Synthesis: Acts as a valuable starting material or chiral auxiliary in stereoselective synthesis for producing enantiomerically pure compounds.
• Academic Research: Utilized in university and institutional labs for chemical education, natural product chemistry studies, and synthetic methodology research.

Basic Information

Product Name	(-)-β-Narcotine
CAS No.	3860-46-6
Molecular Formula	C22H23NO7
Molecular Weight	413.42 g/mol
Synonyms	(-)-Noscapine; L-Narcotine; Narcosine; (-)-1-[(7,8-Dimethoxy-4,5-methylenedioxy-2-phthalanyl)]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; α-Narcotine; Opian; Nectodon; Longatin; Anarcotine; (-)-Narcotine
EINECS	223-352-0

Quality Control

Our (-)-β-Narcotine is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP guidelines where applicable, and our quality assurance process is designed to meet the exacting standards of pharmaceutical and research customers. COAs are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	-200° to -220° (c=1 in CHCl3)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.