Description

3β-[(3-o-Methyl-2,6-Dideoxy-D-Ribo-Hexopyranosyl)Oxy]-14-Hydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. Its value lies in its precise stereochemistry and functional groups, which are essential for developing potent cardiovascular and oncological therapeutics. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel cardiotonic agents and targeted cancer treatments.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel cardiac glycosides and related therapeutic agents.
• Cardiovascular Drug Research: Used in R&D for developing next-generation positive inotropic drugs for heart failure management.
• Oncology Research: Investigated as a precursor for potential anticancer compounds due to its specific inhibitory activity on cellular ion pumps.
• Biochemical Standard: Employed as a high-purity reference standard in analytical laboratories for method development and quality control.
• Mechanistic Studies: Utilized in pharmacological studies to understand the structure-activity relationship (SAR) of Na+/K+-ATPase inhibitors.
• Process Chemistry: Acts as a starting material or intermediate in custom synthesis and process optimization for Active Pharmaceutical Ingredient (API) manufacturing.

Basic Information

Product Name	3β-[(3-o-Methyl-2,6-Dideoxy-D-Ribo-Hexopyranosyl)Oxy]-14-Hydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No.	3751-87-9
Molecular Formula	C30H44O9
Molecular Weight	548.67 g/mol
Synonyms	Gitoxigenin 3-O-methyl-2,6-dideoxy-β-D-ribo-hexopyranoside; 3β-[(3-O-Methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-19-oxo-5β-card-20(22)-enolide; 3-O-Methylgitoxin; Methylgitoxin; 3-Methylgitoxin; 3-O-Methylgitoxigenin glycoside; 3β-[(3-O-Methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3β-[(3-o-Methyl-2,6-Dideoxy-D-Ribo-Hexopyranosyl)Oxy]-14-Hydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.