Description

2,2'-Cyclouridine CAS NO 3736-77-4 is a specialized nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial synthetic intermediate and a valuable scaffold for exploring novel therapeutic agents, particularly in antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of modified nucleosides and nucleotides.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.
• Prodrug Development: Investigated for the design of prodrugs to improve the bioavailability and targeting of nucleoside-based therapies.

Basic Information

Product Name	2,2'-Cyclouridine
CAS No.	3736-77-4
Molecular Formula	C9H12N2O6
Molecular Weight	244.20 g/mol
Synonyms	2,2'-Anhydro-1-β-D-arabinofuranosyluracil; 2,2'-O-Cyclouridine; 1-(2,2-Anhydro-β-D-arabinofuranosyl)uracil; NSC 112907; Uridine, 2,2'-anhydro-; 2,2'-Cyclouridine (2,2'-Anhydrouridine)
EINECS	223-112-6

Quality Control

Our 2,2'-Cyclouridine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) for each batch, detailing key parameters such as assay, purity by HPLC, and identification. Specifications are designed to meet the stringent requirements of research and pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total related substances ≤ 3.0%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.