Description

Tolycaine CAS NO 3686-58-6 is a synthetic local anesthetic agent belonging to the amino amide class. It is valued for its effective nerve-blocking properties and is a key intermediate in pharmaceutical synthesis. This compound is primarily required by manufacturers in the pharmaceutical and life sciences industries for research and development of anesthetic formulations.

Application

• Primary active pharmaceutical ingredient (API) or intermediate in the synthesis of local anesthetic formulations.
• Research and development of novel anesthetic and analgesic drugs in pharmaceutical laboratories.
• As a reference standard in analytical chemistry for quality control and method validation.
• Used in biochemical research to study sodium channel blocking mechanisms.
• Potential use in veterinary medicine for developing topical or injectable anesthetic solutions.

Basic Information

Product Name	Tolycaine
CAS No.	3686-58-6
Molecular Formula	C15H24N2O
Molecular Weight	248.37 g/mol
Synonyms	2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide; 2-Diethylamino-2',6'-acetoxylidide; Diethylglycinexylidide; Tolycaine Hydrochloride; L 67; NSC 113986; Xylocaine Impurity B (related compound)
EINECS	222-989-7

Quality Control

Our Tolycaine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high standards for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.