Description

18-Methylestradiol-3-Methyl Ether is a synthetic steroidal estrogen derivative, recognized for its high purity and consistent performance in advanced research and development. This compound is critical for applications requiring a potent and specific estrogenic reference standard or intermediate. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on endocrinology, steroid chemistry, and novel therapeutic development.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel steroidal drugs and hormone therapies.
• Biochemical Research: Used as a potent ligand in receptor binding assays to study estrogen receptor (ER) affinity and function.
• Academic Studies: Employed in university and institutional labs for investigating estrogen metabolism, structure-activity relationships (SAR), and endocrine pathways.
• Reference Standard Manufacturing: Supplied to certified standards producers for creating high-purity analytical standards used in quality control and regulatory testing.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of more complex steroidal molecules for clinical and pre-clinical evaluation.

Basic Information

Product Name	18-Methylestradiol-3-Methyl Ether
CAS No.	3625-82-9
Molecular Formula	C₂₁H₂₈O₂
Molecular Weight	312.45 g/mol
Synonyms	18-Methylestradiol 3-methyl ether; 3-Methoxy-18-methylestra-1,3,5(10)-trien-17β-ol; 18-Methyl-3-methoxyestra-1,3,5(10)-trien-17β-ol; 18-Methyl-3-methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17β-ol (related IUPAC); 18-ME-3-Me ether; Estra-1,3,5(10)-trien-17β-ol, 3-methoxy-18-methyl-; 18-Methyl-3-methoxyestra-1,3,5(10)-trien-17-ol
EINECS	Contact for details

Quality Control

Our 18-Methylestradiol-3-Methyl Ether is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.