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2-Amino-9-(β-D-2-Deoxyribofuranosyl)Purine CAS NO 3616-24-8


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CAS No.:3616-24-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-9-(β-D-2-Deoxyribofuranosyl)Purine is a high-purity nucleoside analog, a key building block in organic synthesis and pharmaceutical research. Its primary value lies in its role as a versatile intermediate for the development of antiviral and anticancer agents, particularly nucleotide analogs. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors who require reliable, high-quality raw materials for advanced drug discovery and development programs.

Application

  • Pharmaceutical Intermediate: Critical starting material for the synthesis of novel antiviral and anticancer nucleotide analogs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and polymerase function.
  • Antiviral Drug Development: Serves as a core scaffold for the research and production of nucleoside reverse transcriptase inhibitors (NRTIs).
  • Pro-drug Synthesis: Utilized in the creation of pro-drug forms to enhance bioavailability and therapeutic efficacy of active pharmaceutical ingredients (APIs).
  • Labeled Compound Production: Acts as a precursor for synthesizing isotopically labeled (e.g., C13, N15) compounds for metabolic and pharmacokinetic studies.
  • Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental life science research and custom synthesis projects.

Basic Information

Product Name 2-Amino-9-(β-D-2-Deoxyribofuranosyl)Purine
CAS No. 3616-24-8
Molecular Formula C10H13N5O3
Molecular Weight 251.24 g/mol
Synonyms 2-Aminopurine-2'-deoxyriboside; 2-Amino-9-(2-deoxy-β-D-ribofuranosyl)purine; 2-Amino-2'-deoxyadenosine; 2-Aminopurine deoxyriboside; 2-Amino-dA; 2-AP-dR; 2-Aminopurine-2'-deoxyribonucleoside; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine
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Quality Control

Our 2-Amino-9-(β-D-2-Deoxyribofuranosyl)Purine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All batches undergo comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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