Description

3'-Deoxy-N6-Ethyladenosine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and reference standard in the synthesis of novel therapeutic agents, particularly those targeting viral and oncological pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of antiviral and anticancer drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly those involving adenosine deaminase and kinase activity.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Agent Development: Investigated for its potential activity against DNA and RNA viruses due to its modified sugar moiety.
• Oncology Research: Explored for its role in disrupting nucleotide metabolism and DNA synthesis in rapidly dividing cancer cells.
• Labeled Compound Synthesis: A starting material for the preparation of isotopically labeled (e.g., C13, N15) analogs for metabolic tracing studies.

Basic Information

Product Name	3'-Deoxy-N6-Ethyladenosine
CAS No.	3608-60-4
Molecular Formula	C12H17N5O3
Molecular Weight	279.30 g/mol
Synonyms	3'-Deoxy-N6-ethyladenosine; N6-Ethyl-3'-deoxyadenosine; 3'-Deoxy-N(6)-ethyladenosine; Cordycepin N6-ethyl analog; 9-[(2R,5S)-5-(Hydroxymethyl)oxolan-2-yl]-N-ethyl-9H-purin-6-amine; 3'-dA(N6-Et)
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-N6-Ethyladenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all test results are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.