Description

3'-Deoxyguanosine CAS NO 3608-58-0 is a modified nucleoside analog where the hydroxyl group at the 3' position of the ribose sugar is replaced by a hydrogen atom. This structural modification makes it a valuable biochemical building block and research tool for studying nucleic acid metabolism and enzyme mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral research, and the development of diagnostic probes.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for nucleoside kinases and polymerases.
• Antiviral Drug Development: Serves as a key intermediate or analog in the synthesis and screening of potential antiviral compounds.
• Nucleic Acid Chemistry: Acts as a building block for the synthesis of modified oligonucleotides with altered properties.
• Diagnostic Probe Synthesis: Utilized in creating labeled nucleosides for detection and diagnostic assays.
• Metabolic Pathway Studies: Employed to investigate the salvage pathways of purine nucleosides.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3'-Deoxyguanosine
CAS No.	3608-58-0
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	3'-Deoxyguanosine; Cordycepin Impurity C; 9-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-9H-guanine; 2-Amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; Guanosine, 3'-deoxy-; 3'-dG; 3'-Deoxy-G
EINECS	Contact for details

Quality Control

Our 3'-Deoxyguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.